Program Manager

TCR2 Therapeutics Inc. is a preclinical stage immuno-oncology company developing novel cancer therapies that unleash the full signaling power of complete T cell receptors (TCR). TCR2 has developed a unique proprietary TRuC™ platform, which can reprogram the natural TCR complex to recognize specific antigens found on tumors and elicit rapid killing of cancer cells. TRuC-T cells have demonstrated activity against both hematological and solid tumor targets in preclinical models and believes its TRuC™-reprogrammed T cells will serve as the engine for important therapies. TCR2 was founded by MPM Capital and has scientific operations in Cambridge, MA to leverage best-in-class technologies and nucleate top-tier academic laboratories around the world. TCR2 is seeking a creative, resourceful, collaborative program manager to facilitate the delivery of TCR2 revolutionary products to market.

The successful candidate will help to build and manage TCR2's portfolio of therapeutic programs and ensure deliverables fall within the applicable scope and budget. He or she will coordinate with other departments and external collaborators to ensure all aspects of each project are compatible and delivered on time. We are looking for a creative and dedicated individual who will fit with our collaborative culture. If you enjoy working with other professionals who believe in creating innovative solutions to cure cancer, we encourage you to apply. This position represents an excellent opportunity for career development and cross-training in a fast-paced environment. The candidate will report into the Chief Scientific Officer and is expected to provide key support to all departments including research and development, manufacturing, clinical, quality assurance and administrative departments.


  • Develop project scopes and objectives for research and clinical-stage projects, involving all relevant stakeholders
  • Develop detailed project plans to track progress
  • Coordinate internal resources and CROs/CDMOs for the flawless execution of projects
  • Ensure resource availability and allocation
  • Ensure that all projects are delivered on-time, within scope and within budget
  • Prepare regular status reports and escalate to management as needed
  • Manage the relationship with the client and all stakeholders
  • Perform risk management to mitigate timeline shifts
  • Establish and maintain relationships with CROs/vCDMOs
  • Create and maintain comprehensive project documentation


  • Bachelor's Degree in a technical discipline (Engineering, Science or similar)
  • 8+ years experience with at least 3 - 5 years in a technical management role
  • 3-5 years experience in a pharmaceutical manufacturing/development organization
  • Ability to influence at multiple levels (customer, cross-functional team, leadership team) critical to success
  • Proven ability to manage and execute several plans of significant complexity and importance; PMP or equivalent certification
  • Excellent written and verbal communication skills
  • Knowledge and ability to use MS-Office tools, project management tools (MS Project or similar)
  • Management experience in a setting with significant regulatory oversight
  • Consensus building with excellent people management skills
  • Solid organizational skills including attention to detail and multi-tasking skills

Interested candidates should send their resume to